Chapter 2 Drug Discovery, Design, and Development
Silverman R. Chapter 2 Drug Discovery, Design, and Development. 2004, 7-120. DOI: 10.1016/b978-0-08-051337-9.50007-9.Peer-Reviewed Original ResearchDrug designQuantitative structure-activity relationshipQuantitative drug designStructure-activity relationshipDrug discoveryOverview of drug discoverySteric effectsMedicinal chemistsLead compoundsDesign parametersDesignCompoundsRational approachTransport characteristicsMetabolic fatePharmacophorePhysicochemical parametersExpensive processTime-consumingChemistsMoleculesTransportBiological propertiesAverage costCost
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