Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse.
Vosburgh E. Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse. Leukemia 1992, 6: 608-10. PMID: 1602800.Peer-Reviewed Case Reports and Technical NotesConceptsPulmonary leukostasisComplete remissionFirst relapseStandard induction chemotherapyRetinoic acid syndromeRetinoic acidAcute promyelocytic leukemiaAcute promyelocytic leukemia cellsTrans retinoic acidInduction chemotherapyResistant diseaseSignificant leukocytosisClinical trialsLeukostasisPromyelocytic leukemiaPromyelocytic leukemia cellsMature neutrophilsPatientsLeukemia cellsRelapseHigh rateOverall toxicityDe novoRemissionLeukocytosis
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