66 Sugarcane Ash and Sugarcane Ash-Derived Silica Nanoparticles Alter Mitochondrial Function and Metabolic Activity in Human Proximal Tubular Kidney Cells
Stem A, Rogers K, Roncal-Jimenez C, Johnson R, Brown J. 66 Sugarcane Ash and Sugarcane Ash-Derived Silica Nanoparticles Alter Mitochondrial Function and Metabolic Activity in Human Proximal Tubular Kidney Cells. Annals Of Work Exposures And Health 2023, 67: i92-i93. DOI: 10.1093/annweh/wxac087.226.Peer-Reviewed Original ResearchProximal convoluted tubulesDevelopment of CKDuChanges to cellular metabolismChronic kidney diseaseKidney cellsCellular energetic pathwaysEpidemic of chronic kidney diseaseSeahorse XF AnalyzerProximal tubular kidney cellsPCT cellsReduced ATP generationKidney diseaseTubular kidney cellsMetabolomic analysisConvoluted tubulesGlycolytic reserveMitochondrial functionInhibit mitochondrial functionHK-2Promote mitochondrial dysfunctionHours of exposureTreatmentOxygen consumption rateMitochondrial activityMitochondrial dysfunction
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