High-content image-based pooled screens reveal regulators of synaptogenesis
Le A, Biederer T, Blainey P. High-content image-based pooled screens reveal regulators of synaptogenesis. Cell Reports 2025, 44: 115889. PMID: 40560725, DOI: 10.1016/j.celrep.2025.115889.Peer-Reviewed Original ResearchNeuroligin-1High-content screening approachPresynaptic assemblyCell-cell interactionsCytoskeletal dynamicsRegulation of synaptogenesisPhosphatase PTENPooled screeningSynapse inductionCell adhesionSynapse formationSynapse typesScreening platformPhenotypic profileDAG1Adhesion moleculesMolecular interactionsScreening approachSynaptogenesisRegulationSynapseNeuroliginInhibitory synapsesNervous systemPTEN
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