Association of Pulmonary Hemorrhage, Positive Proteinase 3, and Urinary Red Blood Cell Casts With Venous Thromboembolism in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
Kronbichler A, Leierer J, Shin J, Merkel P, Spiera R, Seo P, Langford C, Hoffman G, Kallenberg C, St.Clair E, Brunetta P, Fervenza F, Geetha D, Keogh K, Monach P, Ytterberg S, Mayer G, Specks U, Stone J, Group T. Association of Pulmonary Hemorrhage, Positive Proteinase 3, and Urinary Red Blood Cell Casts With Venous Thromboembolism in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis. Arthritis & Rheumatology 2019, 71: 1888-1893. PMID: 31216123, PMCID: PMC6899947, DOI: 10.1002/art.41017.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisAntibodies, Antineutrophil CytoplasmicErythrocytesFemaleGranulomatosis with PolyangiitisHemorrhageHumansLung DiseasesMaleMicroscopic PolyangiitisMiddle AgedMyeloblastinPeroxidaseProportional Hazards ModelsPulmonary EmbolismRisk FactorsUrineVenous ThromboembolismVenous ThrombosisConceptsRed blood cell castsANCA-associated vasculitisPositive proteinase 3Presence of red blood cell castsVenous thromboembolic eventsVenous thromboembolismCell castsPulmonary hemorrhageHeart involvementPR3-ANCAAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitisAntineutrophil cytoplasmic antibody-associated vasculitisAverage time to eventFactors associated with venous thromboembolismHazard ratioAntibody (ANCA)-associated vasculitisFrequency of venous thromboembolismProteinase 3Mechanisms of hypercoagulabilityAntibody-associated vasculitisPositive PR3-ANCACalculation of hazard ratiosPotential risk factorsRAVE trialOnset of VTE
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