A prospective analysis of germline alterations (GA) in biliary tract cancer (BTC).
Lowery M, Jordan E, Kemel Y, Mukherjee S, Cercek A, Kemeny N, Varghese A, Rusek M, Boucher T, Mandelker D, Berger M, Ptashkin R, Hyman D, Klimstra D, Saltz L, O'Reilly E, Robson M, Stadler Z, Offit K, Abou-Alfa G. A prospective analysis of germline alterations (GA) in biliary tract cancer (BTC). Journal Of Clinical Oncology 2017, 35: 4085-4085. DOI: 10.1200/jco.2017.35.15_suppl.4085.Peer-Reviewed Original ResearchBiliary tract cancerHistory of cancerGermline alterationsPositive family history of cancerProspective analysisFamily history of cancerHereditary cancer predisposition syndromesMatched tumor samplesPersonal history of cancerPositive family historyCancer predisposition syndromeHereditary cancer predispositionIRB-approved protocolMedian ageMSK-IMPACTPredisposition syndromeSomatic alterationsGermline mutationsTumor samplesMismatch repair genesGermline variantsClinical dataFamily historyCancer predispositionDegree relatives
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