2019
Transcriptome-wide piRNA profiling in human gastric cancer
Lin X, Xia Y, Hu D, Mao Q, Yu Z, Zhang H, Li C, Chen G, Liu F, Zhu W, Shi Y, Zhang H, Zheng J, Sun T, Xu J, Chao HH, Zheng X, Luo X. Transcriptome-wide piRNA profiling in human gastric cancer. Oncology Reports 2019, 41: 3089-3099. PMID: 30896887, PMCID: PMC6448102, DOI: 10.3892/or.2019.7073.Peer-Reviewed Original ResearchConceptsPIWI-interacting RNAsTransposable elementsHuman gastric cancerProtein-coding genesNon-coding RNAsCancer risk SNPsPiRNA expressionNearest geneWhole transcriptomeCancer stem cellsDNA variantsIndefinite capacityDifferential expressionAdjacent non-tumorous tissuesStem cellsHuman stomachRegulatory effectsGenesRNANon-tumorous tissuesExpressionMolecular featuresBiological systemsGastric cancerTranscriptome
2014
The C. elegans SNAPc Component SNPC-4 Coats piRNA Domains and Is Globally Required for piRNA Abundance
Kasper DM, Wang G, Gardner KE, Johnstone TG, Reinke V. The C. elegans SNAPc Component SNPC-4 Coats piRNA Domains and Is Globally Required for piRNA Abundance. Developmental Cell 2014, 31: 145-158. PMID: 25373775, PMCID: PMC4223638, DOI: 10.1016/j.devcel.2014.09.015.Peer-Reviewed Original ResearchConceptsRNA genesPIWI-interacting RNA (piRNA) pathwayTransfer RNA genesSmall RNA genesDiscrete genomic regionsDNA-binding subunitSmall nuclear RNAPiRNA abundanceRNA pathwaysPiRNA genesChromatin organizationPiRNA clustersPiRNA expressionProtein complexesGenomic regionsCoordinated expressionNuclear RNAExpression environmentForeign sequencesGenesExpressionDomainPiRNAsLocalizationTransposon
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