Diagnosis of Alzheimer’s disease‐ Analysis of cross‐species biomarkers
Bathla S. Diagnosis of Alzheimer’s disease‐ Analysis of cross‐species biomarkers. Alzheimer's & Dementia 2024, 20: e095406. PMCID: PMC11712473, DOI: 10.1002/alz.095406.Peer-Reviewed Original ResearchEntorhinal cortexAD patientsP-tauTau pathologyAged rhesus monkeysDKI miceQuantitative phospho-proteomicsPrefrontal cortexStages of ADAntibody-free methodAged monkeysMultifactorial neurodegenerative disorderChronic treatmentNon-human primatesAged rhesus macaquesMouse tauEnvironmental linksPhospho-proteomicsPhosphorylation sitesTau hyperphosphorylationRhesus monkeysP-tau181 concentrationsWestern blot analysisLumipulse platformCortexA Unified Post-Transcriptional Mechanism Regulates Intron Retention in Splicing Factor-Mutant MDS
Boddu P, Roy R, Baumgartner F, Hutter S, Haferlach T, Pillai M. A Unified Post-Transcriptional Mechanism Regulates Intron Retention in Splicing Factor-Mutant MDS. Blood 2024, 144: 2732-2732. DOI: 10.1182/blood-2024-211458.Peer-Reviewed Original ResearchRNA-binding proteinsIntron retentionAlternative splicing patternsPost-transcriptional mechanismsIR eventsSF mutationsSR proteinsSF3B1 mutantsAnalyzed RNA-seq datasetsMyelodysplastic syndromeCo-transcriptional splicingCo-transcriptional mechanismsRNA-seq datasetsPost-transcriptional splicingWild-typeSub-compartmentsNuclear sub-compartmentsHEK293T cellsGene expression analysisWild-type K562 cellsRNA processingMutant cellsPhospho-proteomicsExon featuresAS events
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply