Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C
Sim MJ, Malaker SA, Khan A, Stowell JM, Shabanowitz J, Peterson ME, Rajagopalan S, Hunt DF, Altmann DM, Long EO, Boyton RJ. Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C. Frontiers In Immunology 2017, 8: 193. PMID: 28352266, PMCID: PMC5348643, DOI: 10.3389/fimmu.2017.00193.Peer-Reviewed Original ResearchKiller cell immunoglobulin-like receptorsImpact of HLAHLA-C allotypesCross-reactive bindingHLA-C allelesHuman natural killer cell activityInhibitory killer cell immunoglobulin-like receptorsNatural killer cell activityNK cell inhibitory receptorsHIV Gag peptidesKiller cell activityNK cell functionNK cell activationNK cell biologyEndogenous peptidesDisorders of pregnancyImmunoglobulin-like receptorsCell inhibitory receptorsSpecific bindingKIR specificityGag peptidesInhibitory receptorsHLA genotypeKIR-HLAPeptide dependence
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