2017
Immune marker profiling and PD-L1, PD-L2 expression mechanisms across non-small cell lung cancer mutations.
Toki M, Mani N, Smithy J, Liu Y, Altan M, Wasserman B, Tuktamyshov R, Syrigos K, Rimm D. Immune marker profiling and PD-L1, PD-L2 expression mechanisms across non-small cell lung cancer mutations. Journal Of Clinical Oncology 2017, 35: 9076-9076. DOI: 10.1200/jco.2017.35.15_suppl.9076.Peer-Reviewed Original ResearchNon-small cell lung cancerEpidermal growth factor receptorPD-L1 expressionPD-L2 expressionPD-L1Stroma expressionTIL activationKRAS mutantPD-1/PD-L1 axis inhibitorsMutation statusResponse rateProximity ligation assayHigh PD-L1 levelsActivation statusProgrammed Death Ligand 1EGFR mutantsHigh PD-L1NSCLC patient tumorsTherapy response ratesPD-L1 levelsDeath ligand 1Cell lung cancerEGFR-mutant tumorsPD-L1 tumorsHigh response rate
2016
Meta-analysis of tumor PD-L1 expression as a predictive biomarker of benefit from PD-1/PD-L1 axis inhibitors in solid tumors.
Khunger M, Rakshit S, Schalper K, Elson P, Pennell N, Stevenson J, Velcheti V. Meta-analysis of tumor PD-L1 expression as a predictive biomarker of benefit from PD-1/PD-L1 axis inhibitors in solid tumors. Journal Of Clinical Oncology 2016, 34: 11603-11603. DOI: 10.1200/jco.2016.34.15_suppl.11603.Peer-Reviewed Original ResearchPD-1/PD-L1 axis inhibitorsTumor PD-L1 expressionPD-L1 expressionPredictive biomarkersSolid tumorsTumors
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