Increased fear‐ and stress‐related anxiety‐like behavior in mice lacking tuberoinfundibular peptide of 39 residues
Fegley DB, Holmes A, Riordan T, Faber CA, Weiss JR, Ma S, Batkai S, Pacher P, Dobolyi A, Murphy A, Sleeman MW, Usdin TB. Increased fear‐ and stress‐related anxiety‐like behavior in mice lacking tuberoinfundibular peptide of 39 residues. Genes Brain & Behavior 2008, 7: 933-942. PMID: 18700839, PMCID: PMC2605196, DOI: 10.1111/j.1601-183x.2008.00432.x.Peer-Reviewed Original ResearchConceptsAnxiety-like behaviorAnxiety-related behaviorTuberoinfundibular peptideElevated plus-maze assayParathyroid hormone 2 receptorMedial paralemniscal nucleusGreater anxiety-like behaviorPavlovian fear conditioning paradigmShock-probe testGroups of neuronsMedial prefrontal cortexSubparafascicular areaNeurons projectAnxiety-related phenotypesLateral brainstemParalemniscal nucleusLateral septumBed nucleusStria terminalisFear conditioning paradigmEnvironmental provocationTargeted null mutationBrain regionsFear extinctionPrefrontal cortex
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