2013
Chapter 66 Disorders of Calcium Metabolism
Dumitru C, Wysolmerski J. Chapter 66 Disorders of Calcium Metabolism. 2013, 2273-2309. DOI: 10.1016/b978-0-12-381462-3.00066-5.Peer-Reviewed Original ResearchCalcium metabolismCalcium levelsParathyroid hormone-related proteinMulti-organ dysfunctionHormone-related proteinMetabolic bone disordersExtracellular calcium levelsParathyroid hormone receptorPrinciples of managementParathyroid hormoneBone metabolismBone disordersPrevalent causeCalcium homeostasisOrgan systemsHormone receptorsDisease statesHypercalcemiaHypocalcemiaDisordersNormal regulationHormoneMetabolismReceptorsCritical role
2000
Functional parathyroid hormone receptors are present in an umbilical vein endothelial cell line
Isales C, Sumpio B, Bollag R, Zhong Q, Ding K, Du W, Rodriguez-Commes J, Lopez R, Rosales O, Gasalla-Herraiz J, McCarthy R, Barrett P. Functional parathyroid hormone receptors are present in an umbilical vein endothelial cell line. AJP Endocrinology And Metabolism 2000, 279: e654-e662. PMID: 10950835, DOI: 10.1152/ajpendo.2000.279.3.e654.Peer-Reviewed Original ResearchMeSH KeywordsCalciumCell LineChromatography, High Pressure LiquidCyclic AMPEndothelin-1Endothelium, VascularFluorescent DyesFura-2Glyceraldehyde-3-Phosphate DehydrogenasesHumansInositol PhosphatesParathyroid HormoneReceptors, Parathyroid HormoneReverse Transcriptase Polymerase Chain ReactionRNA, MessengerSignal TransductionThymidineUmbilical VeinsConceptsParathyroid hormoneUmbilical vein endothelial cell lineParathyroid hormone receptorEndothelial cell lineHormone receptorsVascular smooth muscle relaxationEndothelin-1 secretionSmooth muscle relaxationVascular smooth muscleHuman umbilical vein endothelial cell lineCell linesCellular cAMP contentPossible direct effectPeptide receptor mRNAEndothelium-derived cellsBlood pressureContinuous infusionMuscle relaxationIntracellular calciumSmooth muscleReceptor mRNAHormone exposureVascular endotheliumEndothelial cellsCAMP content
1996
Parathyroid Hormone-Related Protein: From Hypercalcemia of Malignancy to Developmental Regulatory Molecule
Dunbar M, Wysolmerski J, Broadus A. Parathyroid Hormone-Related Protein: From Hypercalcemia of Malignancy to Developmental Regulatory Molecule. The American Journal Of The Medical Sciences 1996, 312: 287-294. DOI: 10.1016/s0002-9629(15)41844-0.Peer-Reviewed Original ResearchConceptsDevelopmental regulatory moleculeCommon metabolic complicationHypercalcemia of malignancyHormone-related proteinParathyroid hormone receptorTypes of cancerMetabolic complicationsHumoral hypercalcemiaParathyroid hormoneRegulatory moleculesParacrine fashionBiochemical manifestationsMalignant cellsHypercalcemiaFetal tissuesPTHrPHormone receptorsNormal biological functionsMalignancyMolecular evolutionHHMBiological functionsMolecular mechanismsComplicationsKidneyParathyroid Hormone-Related Protein: From Hypercalcemia of Malignancy to Developmental Regulatory Molecule
Dunbar M, Wysolmerski J, Broadus A. Parathyroid Hormone-Related Protein: From Hypercalcemia of Malignancy to Developmental Regulatory Molecule. The American Journal Of The Medical Sciences 1996, 312: 287-294. PMID: 8969618, DOI: 10.1097/00000441-199612000-00007.Peer-Reviewed Original ResearchConceptsDevelopmental regulatory moleculeCommon metabolic complicationHypercalcemia of malignancyHormone-related proteinParathyroid hormone receptorTypes of cancerMetabolic complicationsHumoral hypercalcemiaParathyroid hormoneRegulatory moleculesParacrine fashionBiochemical manifestationsMalignant cellsHypercalcemiaFetal tissuesPTHrPHormone receptorsNormal biological functionsMalignancyMolecular evolutionHHMBiological functionsMolecular mechanismsComplicationsKidneyFull Activation of Chimeric Receptors by Hybrids between Parathyroid Hormone and Calcitonin EVIDENCE FOR A COMMON PATTERN OF LIGAND-RECEPTOR INTERACTION*
Bergwitz C, Gardella T, Flannery M, Potts J, Kronenberg H, Goldring S, Jüppner H. Full Activation of Chimeric Receptors by Hybrids between Parathyroid Hormone and Calcitonin EVIDENCE FOR A COMMON PATTERN OF LIGAND-RECEPTOR INTERACTION*. Journal Of Biological Chemistry 1996, 271: 26469-26472. PMID: 8900113, DOI: 10.1074/jbc.271.43.26469.Peer-Reviewed Original ResearchConceptsParathyroid hormoneG protein-coupled receptorsProtein-coupled receptorsReceptor chimerasPTH receptorFamily of G protein-coupled receptorsLigand-receptor interactionsPatterns of ligand-receptor interactionsCalcitoninParathyroid hormone receptorReceptorsCommon patternChimeric receptorsHormoneHybrid ligandsAmino acid sequence homologyFull activationSame family
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply