Normal Lytic Granule Secretion by Cytotoxic T Lymphocytes Deficient in BLOC‐1, ‐2 and ‐3 and Myosins Va, VIIa and XV
Bossi G, Booth S, Clark R, Davis E, Liesner R, Richards K, Starcevic M, Stinchcombe J, Trambas C, Dell'Angelica E, Griffiths G. Normal Lytic Granule Secretion by Cytotoxic T Lymphocytes Deficient in BLOC‐1, ‐2 and ‐3 and Myosins Va, VIIa and XV. Traffic 2005, 6: 243-251. PMID: 15702992, DOI: 10.1111/j.1600-0854.2005.00264.x.Peer-Reviewed Original ResearchConceptsCytotoxic T lymphocytesBLOC-1Mouse model of Hermansky-Pudlak syndromeModel of Hermansky-Pudlak syndromeT lymphocytesLysosome-related organellesLytic granule secretionCytotoxic T lymphocyte functionPale ear miceUnconventional myosinBLOC-3Protein machineryBLOC-2Myosin VaSecretory lysosomesSecretory organellesAP-3Ruby-eyeHermansky-Pudlak syndromeDisplay defectsHPS patientsGranule secretionPlatelet functionSandy miceMouse model
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