Effects of sub-chronic methylphenidate on risk-taking and sociability in zebrafish (Danio rerio)
Brenner R, Oliveri A, Sinnott-Armstrong W, Levin E. Effects of sub-chronic methylphenidate on risk-taking and sociability in zebrafish (Danio rerio). Naunyn-Schmiedeberg's Archives Of Pharmacology 2020, 393: 1373-1381. PMID: 32025747, PMCID: PMC7716188, DOI: 10.1007/s00210-020-01835-z.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderSub-chronic dosesTreated with stimulant medicationVisual stimuliDecreased locomotor responseEffects of methylphenidateDeficit hyperactivity disorderRisk-takingImpaired avoidanceLocomotor responseAvoidance paradigmMethylphenidate exposureSocial stimuliStimulant medicationPsychiatric disordersHyperactivity disorderBehavioral functionsMethylphenidateNovel tankNeurobehavioral impairmentsDosing paradigmNeurobehavioral toxicityDecreased activity levelsAdult zebrafishStimuli
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