Expression of complement C3, C5, C3aR and C5aR1 genes in resting and activated CD4+ T cells
Hansen C, Willer A, Bayarri-Olmos R, Kemper C, Garred P. Expression of complement C3, C5, C3aR and C5aR1 genes in resting and activated CD4+ T cells. Immunobiology 2018, 224: 307-315. PMID: 30612786, DOI: 10.1016/j.imbio.2018.12.004.Peer-Reviewed Original ResearchConceptsT cellsComplement proteinsComplement C3Dependent mechanismLow-grade expressionTime pointsActivation of CD4Non-activated T-cellsNormal T cellsExpression levelsT cell activationMRNA expression levelsDifferent time pointsNormal CD4Intracellular C3Normal donorsCD4Intracellular complementIntracellular storesComplement activationC3aRIntracellular expressionIncubation time pointsMRNA levelsQuantitative PCR technique
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