Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells
Hendry S, van der Bogt K, Sheikh A, Arai T, Dylla S, Drukker M, McConnell M, Kutschka I, Hoyt G, Cao F, Weissman I, Connolly A, Pelletier M, Wu J, Robbins R, Yang P. Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. Journal Of Thoracic And Cardiovascular Surgery 2008, 136: 1028-1037.e1. PMID: 18954646, DOI: 10.1016/j.jtcvs.2007.12.053.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDisease Models, AnimalEmbryonic Stem CellsFemaleFibroblastsGraft RejectionGraft SurvivalImmunohistochemistryMagnetic Resonance ImagingMiceMice, SCIDMyocardial ContractionMyocardial InfarctionMyocytes, CardiacRandom AllocationReproducibility of ResultsSensitivity and SpecificityStem Cell TransplantationStroke VolumeVentricular RemodelingConceptsEmbryonic stem cellsMagnetic resonance imagingIn vivo magnetic resonance imagingMouse embryonic stem cellsStem cellsResonance imagingMyocardial restorationIn vivo pressure-volume loopsPolymerase chain reactionLeft ventricular ejection fractionBioluminescence imagingSCID-beige miceVentricular ejection fractionEmbryonic stem cell groupStem cell groupMouse embryonic fibroblastsChain reactionIn vivo bioluminescence imagingCoronary artery ligationAssessment of functional recoveryAntifibrotic genesAcute myocardial infarctionDiastolic functionEjection fractionCardiac phenotype
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