Spinal cord α2-adrenoceptors may be located postsynaptically with respect to primary sensory neurons: Destruction of primary C-afferents with neonatal capsaicin does not affect the number of [3H]clonidine binding sites in mice
Wikberg J, Hajós M. Spinal cord α2-adrenoceptors may be located postsynaptically with respect to primary sensory neurons: Destruction of primary C-afferents with neonatal capsaicin does not affect the number of [3H]clonidine binding sites in mice. Neuroscience Letters 1987, 76: 63-68. PMID: 3035432, DOI: 10.1016/0304-3940(87)90193-5.Peer-Reviewed Original ResearchConceptsPrimary sensory neuronsSpinal cordSensory neuronsFmol/Capsaicin-treated animalsAfferent C-fibersNeonatal capsaicinNociceptive transmissionC-afferentsPain sensitivityC-fibersControl animalsCapsaicinMarked reductionSelective lossSecond dayContent of alphaCordAlphaMiceNeuronsLarge proportionAnimalsClonidineAgonists
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