2020
Approach Coping and Substance Use Outcomes Following Mindfulness-Based Relapse Prevention Among Individuals with Negative Affect Symptomatology
Roos C, Bowen S, Witkiewitz K. Approach Coping and Substance Use Outcomes Following Mindfulness-Based Relapse Prevention Among Individuals with Negative Affect Symptomatology. Mindfulness 2020, 11: 2397-2410. PMID: 33510820, PMCID: PMC7837604, DOI: 10.1007/s12671-020-01456-w.Peer-Reviewed Original ResearchSubstance use disordersAffective symptomsRelapse preventionSubstance-related problemsTherapeutic effectConditional indirect effectsHeavy drinking daysApproach copingAvoidance copingSubstance use outcomesNegative affective symptomsMonth 12Conditional indirect effect modelDrinking daysUse disordersSignificant conditional indirect effectAftercare treatmentSymptomsAffective symptomatologyLatent growth curve analysisIndirect effects modelPTSD symptomsCurve analysisMethodsThe sampleSubstance useAltered frontal cortex functioning in emotion regulation and hopelessness in bipolar disorder
Sankar A, Purves K, Colic L, Lippard ETC, Millard H, Fan S, Spencer L, Wang F, Pittman B, Constable RT, Gross JJ, Blumberg HP. Altered frontal cortex functioning in emotion regulation and hopelessness in bipolar disorder. Bipolar Disorders 2020, 23: 152-164. PMID: 32521570, PMCID: PMC7790437, DOI: 10.1111/bdi.12954.Peer-Reviewed Original ResearchConceptsExplicit emotion regulationEmotion regulationBrain responsesMood statesDorsal anterior cingulate cortexEmotion regulation difficultiesHappy facial stimuliFrontal cortex functioningDorsal frontal regionsBipolar disorderAcute mood symptomsAnterior cingulate cortexFunctional MRI dataMajor suicide risk factorsNegative affective symptomsEuthymic mood stateRegional brain responsesFacial stimuliRegulation difficultiesFrontal engagementMOFC responseNegative emotionsLoss of motivationDiminished motivationEuthymic individuals
2017
Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse
Toma W, Kyte S, Bagdas D, Alkhlaif Y, Alsharari S, Lichtman A, Chen Z, Del Fabbro E, Bigbee J, Gewirtz D, Damaj M. Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse. Neuropharmacology 2017, 117: 305-315. PMID: 28237807, PMCID: PMC5489229, DOI: 10.1016/j.neuropharm.2017.02.020.Peer-Reviewed Original ResearchConceptsCancer chemotherapeutic drugsCancer patientsPreclinical modelsSide effectsAffective symptomsMajor dose-limiting side effectDose-limiting side effectChemotherapeutic drugsLight/dark box testNerve fiber dysfunctionPaclitaxel-treated miceProgression-free survivalSucrose preference testDepression-like behaviorOvarian cancer patientsSevere side effectsAnxiety-like behaviorPotential therapeutic interventionsEffect of paclitaxelAnhedonia-like stateDark box testCold allodyniaNeuropathic painNegative affective symptomsNociceptive effects
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