2024
Pharmacological management of gambling disorder: an update of the literature
Mestre-Bach G, Potenza M. Pharmacological management of gambling disorder: an update of the literature. Expert Review Of Neurotherapeutics 2024, 24: 391-407. PMID: 38357896, DOI: 10.1080/14737175.2024.2316833.Peer-Reviewed Original ResearchGambling disorderCo-occurring disordersSerotonin reuptake inhibitorsPlacebo response ratesOpioid receptor antagonistMental health conditionsGlutamatergic agentsNeurobiological correlatesGambling subtypesMood stabilizersReuptake inhibitorsClasses of medicationsPharmacological treatmentBetting behaviorGamblingTreatment responsePharmacological interventionsDisordersPharmacological managementMedicationTreatment optionsNarrative reviewLongitudinal informationResponse rateNalmefene
2008
Effects of Opioid Receptor Gene Variation on Targeted Nalmefene Treatment in Heavy Drinkers
Arias AJ, Armeli S, Gelernter J, Covault J, Kallio A, Karhuvaara S, Koivisto T, Mäkelä R, Kranzler HR. Effects of Opioid Receptor Gene Variation on Targeted Nalmefene Treatment in Heavy Drinkers. Alcohol Clinical And Experimental Research 2008, 32: 1159-1166. PMID: 18537939, PMCID: PMC2950972, DOI: 10.1111/j.1530-0277.2008.00735.x.Peer-Reviewed Original ResearchConceptsOpioid receptor geneSingle nucleotide polymorphismsTherapeutic effectReceptor geneHeavy drinkingOpioid antagonist nalmefenePlacebo-controlled trialKappa-opioid receptorsNaltrexone treatment responseHeavy drinking daysReceptor gene polymorphismsOpioid receptor gene polymorphismsAsn40Asp polymorphismNalmefene treatmentPolymorphic variationAntagonist treatmentMedication responseTreatment responsePharmacogenetic analysisReceptor gene variationDrinking daysNalmefeneGene polymorphismsHeavy drinkersConflicting results
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