2015
CD90 and CD105 expression in the mouse ovary and testis at different stages of postnatal development
Tepekoy F, Ozturk S, Sozen B, Ozay R, Akkoyunlu G, Demir N. CD90 and CD105 expression in the mouse ovary and testis at different stages of postnatal development. Reproductive Biology 2015, 15: 195-204. PMID: 26679159, DOI: 10.1016/j.repbio.2015.10.004.Peer-Reviewed Original ResearchConceptsExpression of CD90Postnatal developmentGerm cellsPostnatal dayCell typesSomatic cellsGerm cell compartmentMesenchymal stem cell markersStem cell markersStages of gonadal developmentStages of postnatal developmentExpression of CD105Female gonadal cellsMouse gonadsSertoli cellsPostnatal gonadsTesticular expressionMouse ovariesGonadal cellsCD105 expressionCell markersGonadal developmentAdult ovariesImmunohistochemical localizationCD105
2014
Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries
Ozturk S, Sozen B, Demir N. Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries. Journal Of Assisted Reproduction And Genetics 2014, 32: 137-146. PMID: 25370180, PMCID: PMC4294878, DOI: 10.1007/s10815-014-0362-5.Peer-Reviewed Original ResearchConceptsPostnatal mouse ovariesCumulus-oocyte complexesMouse ovariesPABPC1 genePrepubertal ovariesGranulosa cellsGerm cellsPrepubertal mouse ovariesEarly preimplantation embryosOvarian follicle countsCytoplasm of oocytesRNA in situ hybridizationReal-time polymerase chain reactionVertebrate germ cellsExpression levelsMII oocytesOocyte complexesPostnatal ovaryCumulus cellsPreimplantation embryosFollicle countPABPC1 expressionQuantitative real-time polymerase chain reactionPolymerase chain reactionFollicular stage
2013
Characterization of the Gonadotropin Releasing Hormone Receptor (GnRHR) Expression and Activity in the Female Mouse Ovary
Torrealday S, Lalioti MD, Guzeloglu-Kayisli O, Seli E. Characterization of the Gonadotropin Releasing Hormone Receptor (GnRHR) Expression and Activity in the Female Mouse Ovary. Endocrinology 2013, 154: 3877-3887. PMID: 23913446, PMCID: PMC3776864, DOI: 10.1210/en.2013-1341.Peer-Reviewed Original ResearchConceptsGranulosa/cumulus cellsGranulosa cellsMouse ovariesReceptor expressionPrimary mouse granulosa cellsCumulus cellsPregnant mare serum gonadotropinIntracellular cAMPHormone receptor expressionGnRH receptor expressionCultured granulosa cellsOvarian granulosa cellsMouse granulosa cellsMechanism of actionGonadotoxic chemotherapyQuantitative RT-PCRGnRH agonistGnRHR mRNAFertility preservationMouse pituitary cellsLuciferase reporter plasmidSerum gonadotropinPituitary cell linePituitary cellsPituitary tissue
2012
Prevention of chemotherapy-induced damage to ovarian reserve by sphingosine-1-phosphate
LI F, Ozkaya E, Akula K, Desutter P, Oktay K. Prevention of chemotherapy-induced damage to ovarian reserve by sphingosine-1-phosphate. Journal Of Clinical Oncology 2012, 30: 1097-1097. DOI: 10.1200/jco.2012.30.15_suppl.1097.Peer-Reviewed Original ResearchFollicle deathOvarian functionApoptotic folliclesOvarian reserveChemotherapy agentsPrimordial folliclesMini-osmotic pumpsOld NOD miceChemotherapy-induced damageAssisted reproduction techniquesSphingosine-1-PhosphateChemotherapy injectionsNOD miceContinuous infusionTotal folliclesPharmacological meansD groupS1P treatmentMouse ovariesPathway inhibitorCytotoxic agentsFolliclesS1PDeathSignificant decrease
2008
Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics
Szotek P, Chang H, Brennand K, Fujino A, Pieretti-Vanmarcke R, Celso C, Dombkowski D, Preffer F, Cohen K, Teixeira J, Donahoe P. Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 12469-12473. PMID: 18711140, PMCID: PMC2527935, DOI: 10.1073/pnas.0805012105.Peer-Reviewed Original ResearchConceptsLabel-retaining cell populationStem/progenitor cellsSomatic stem/progenitor cellsEpithelial label-retaining cellsCoelomic epitheliumProgenitor cellsCell populationsCell-mediated processStem/progenitor cell characteristicsLabel-retaining cellsEstrous cyclingAdult miceProgenitor cell characteristicsMouse ovariesCytoprotective mechanismsSide population
2000
Interaction of Extracellular Matrix and Activin-A in the Initiation of Follicle Growth in the Mouse Ovary1
Oktay K, Karlikaya G, Akman O, Ojakian G, Oktay M. Interaction of Extracellular Matrix and Activin-A in the Initiation of Follicle Growth in the Mouse Ovary1. Biology Of Reproduction 2000, 63: 457-461. PMID: 10906050, DOI: 10.1095/biolreprod63.2.457.Peer-Reviewed Original ResearchConceptsFollicle growth initiationFollicle developmentFollicle growthFollicle growth rateFollicle densityRecombinant human activinEarly follicle developmentEarly follicular developmentRole of activinAbsence of activinTotal folliclesFollicular growthExtracellular matrixFollicular developmentTreatment groupsMultilayer folliclesMouse ovariesActivin treatmentHuman activinPresence of lamininActivinExtracellular matrix componentsPrecise mechanismMiceFollicles
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