Recent advances of animal model of focal segmental glomerulosclerosis
Yang J, Dettmar A, Kronbichler A, Gee H, Saleem M, Kim S, Shin J. Recent advances of animal model of focal segmental glomerulosclerosis. Clinical And Experimental Nephrology 2018, 22: 752-763. PMID: 29556761, DOI: 10.1007/s10157-018-1552-8.Peer-Reviewed Original ResearchConceptsAnimal models of focal segmental glomerulosclerosisFocal segmental glomerulosclerosisGroups of animal modelsModel of focal segmental glomerulosclerosisAnimal modelsSegmental glomerulosclerosisCD2-associated proteinCombination of genetic mutationsPathophysiology of focal segmental glomerulosclerosisGenetic engineering techniquesStudy focal segmental glomerulosclerosisGene disruptionGenetic basisGenetic animal modelsHuman diseasesTRPC6 channelsRenal ablationPodocyte toxinGenetic mutationsComplex pathophysiologyMouse backgroundSlit diaphragmDiphtheria toxinPodocyte injuryAdaptive response
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