Probiotic Lactobacilli Ameliorate Antibiotic-Induced Cognitive and Behavioral Impairments in Mice
Yarullina D, Novoselova V, Alexandrova A, Arslanova A, Yakovleva O, Shaidullov I, Nikolaev Y, El-Registan G, Kudrin V, Sitdikova G. Probiotic Lactobacilli Ameliorate Antibiotic-Induced Cognitive and Behavioral Impairments in Mice. Microbiology Research 2024, 15: 1471-1485. DOI: 10.3390/microbiolres15030099.Peer-Reviewed Original ResearchObject recognition testOpen field testMetabolite 5-hydroxyindoleacetic acidNovel object recognition testAnxiety-related behaviorT-maze testGut microbiotaInfluence brain functionMicrobiota-gut-brain axisMicrobiota-gut-brainAntibiotic-inducedRegulating anxietyT-mazeRecognition testExploratory activityCognitive abilitiesBehavioral disordersBehavioral testsAntibiotic-treated miceFerrous oxidation-xylenol orange (FOX) assayBrain functionProbiotic lactobacilli strainsMRS brothLactobacilli strainsAdministration of probioticsGut microbiota-derived short-chain fatty acids and depression: deep insight into biological mechanisms and potential applications
Cheng J, Hu H, Ju Y, Liu J, Wang M, Liu B, Zhang Y. Gut microbiota-derived short-chain fatty acids and depression: deep insight into biological mechanisms and potential applications. General Psychiatry 2024, 37: e101374. PMID: 38390241, PMCID: PMC10882305, DOI: 10.1136/gpsych-2023-101374.Peer-Reviewed Original ResearchShort-chain fatty acidsMicrobiota-gut-brain axisGut microbiotaGut microbiota-derived short-chain fatty acidsMicrobiota-derived short-chain fatty acidsFatty acidsHost epigenomeBiological mechanismsMicrobiotaBioactive metabolitesDynamic ecosystemsGutImmune pathwaysPathophysiology of depressionChronic cerebral hypoperfusionCentral nervous systemNeuroendocrine alterationsClinical valueEpigenomeCerebral hypoperfusionNeuropsychiatric disordersMetabolitesDisease statusNervous systemDepression
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