Anti-neuroinflammatory effects of the KIOM -patented Polygonum multiflorum maximized root tuber against LPS-stimulated BV2 Cells
Oh T, Ban Y, Kang Y. Anti-neuroinflammatory effects of the KIOM -patented Polygonum multiflorum maximized root tuber against LPS-stimulated BV2 Cells. Applied Biological Chemistry 2024, 67: 71. DOI: 10.1186/s13765-024-00928-0.Peer-Reviewed Original ResearchHigher content of active ingredientP. multiflorumMouse microglial BV-2 cellsLPS-stimulated BV2 cellsContent of active ingredientsTranscription factor activityAnti-neuroinflammatory effectsMitogen-activated protein kinaseMechanisms of neurodegenerationActivation of p38Pathological mechanisms of neurodegenerationMicroglial BV-2 cellsHigher contentIncreased biomassRoot tubersBV2 cellsAntioxidant effectsCultivation conditionsProtein kinaseOriental medicinal herbRegulation mechanismBV-2 cellsInducible NO synthaseMAPK phosphorylationMedicinal herbs
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