2022
Clinical utility of next-generation sequencing for prostate cancer in the context of a changing treatment landscape.
Griffin J, Jun T, Liaw B, Guin S, Tsao C, Patel V, Rossi M, Zhou X, Hantash F, Chen R, Oh W. Clinical utility of next-generation sequencing for prostate cancer in the context of a changing treatment landscape. Journal Of Clinical Oncology 2022, 40: 112-112. DOI: 10.1200/jco.2022.40.6_suppl.112.Peer-Reviewed Original ResearchProstate cancerClinical utilityPCa patientsActionable alterationsTreatment landscapeNext-generation sequencingFDA approvalPARP inhibitorsSingle-center retrospective cohortRetrospective single-center studySingle academic medical centerHomologous recombination repair genesAlternative systemic therapiesUnknown treatment statusProportion of patientsSingle-center studyMetastatic PCa patientsMetastatic prostate cancerMount Sinai HospitalSolid tumor panelAcademic medical centerElectronic medical recordsRecombination repair genesMedian TTNTMetastatic patients
2019
Germline Genetic Testing in Advanced Prostate Cancer; Practices and Barriers: Survey Results from the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium
Paller CJ, Antonarakis ES, Beer TM, Borno HT, Carlo MI, George DJ, Graff JN, Gupta S, Heath EI, Higano CS, McKay RR, Morgans AK, Patnaik A, Petrylak DP, Rettig MB, Ryan CJ, Taplin ME, Whang YE, Vinson J, Cheng HH, Giri VN, Group P. Germline Genetic Testing in Advanced Prostate Cancer; Practices and Barriers: Survey Results from the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium. Clinical Genitourinary Cancer 2019, 17: 275-282.e1. PMID: 31171481, PMCID: PMC6662206, DOI: 10.1016/j.clgc.2019.04.013.Peer-Reviewed Original ResearchConceptsProstate Cancer Clinical Trials ConsortiumGermline genetic testingClinical Trials ConsortiumGenetic testingPCa patientsAdvanced prostate cancer patientsAdvanced prostate cancerMetastatic PCa patientsClinical trial eligibilityProstate cancer patientsPan-cancer panelCancer gene panelTrial eligibilityChoice of assayLocal diseaseCancer CenterAcademic oncologistsCancer patientsProstate cancerCancer treatment facilitiesPatientsBusy clinicPrecision therapyPersonalized treatmentWorking Group
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