2018
The Germline-Specific Factor OEF-1 Facilitates Coordinated Progression Through Germ Cell Development in Caenorhabditis elegans
McManus CE, Reinke V. The Germline-Specific Factor OEF-1 Facilitates Coordinated Progression Through Germ Cell Development in Caenorhabditis elegans. Genetics 2018, 208: 549-563. PMID: 29167199, PMCID: PMC5788521, DOI: 10.1534/genetics.117.1123.Peer-Reviewed Original ResearchConceptsGerm cell developmentGerm cellsCell developmentGermline-expressed genesNovel nuclear proteinCell cycle checkpointsGermline expressionGenomic integrityUnique fateOocyte differentiationFaithful transmissionCycle checkpointsNuclear proteinsMature gametesX chromosomeDevelopmental eventsLarval stagesMaturation eventsGenetic materialCaenorhabditisFactor 1Developmental progressionSubtle defectsCellsExpression
2006
In vitro generation of germ cells from murine embryonic stem cells
West JA, Park IH, Daley GQ, Geijsen N. In vitro generation of germ cells from murine embryonic stem cells. Nature Protocols 2006, 1: 2026-2036. PMID: 17487192, DOI: 10.1038/nprot.2006.303.Peer-Reviewed Original ResearchConceptsPutative primordial germ cellsEmbryonic stem cellsMurine embryonic stem cellsGerm cellsPrimordial germ cellsGerm cell developmentEmbryoid body differentiationHaploid male gametesStem cellsImprint erasureEpigenetic phenomenaGamete formationHaploid cellsGamete developmentMature gametesMale gametesStages of differentiationDifferentiation systemBody differentiationGerm layersCell developmentAggregates of cellsSpontaneous differentiationTeratoma formationCell allocation
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