The Integrated Genomic Landscape of Thymic Epithelial Tumors
Radovich M, Pickering CR, Felau I, Ha G, Zhang H, Jo H, Hoadley KA, Anur P, Zhang J, McLellan M, Bowlby R, Matthew T, Danilova L, Hegde AM, Kim J, Leiserson MDM, Sethi G, Lu C, Ryan M, Su X, Cherniack AD, Robertson G, Akbani R, Spellman P, Weinstein JN, Hayes DN, Raphael B, Lichtenberg T, Leraas K, Zenklusen JC, Network T, Ally A, Appelbaum E, Auman J, Balasundaram M, Balu S, Behera M, Beroukhim R, Berrios M, Blandino G, Bodenheimer T, Bootwalla M, Bowen J, Brooks D, Carcano F, Carlsen R, Carvalho A, Castro P, Chalabreysse L, Chin L, Cho J, Choe G, Chuah E, Chudamani S, Cibulskis C, Cope L, Cordes M, Crain D, Curley E, Defreitas T, Demchok J, Detterbeck F, Dhalla N, Dienemann H, Edenfield W, Facciolo F, Ferguson M, Frazer S, Fronick C, Fulton L, Fulton R, Gabriel S, Gardner J, Gastier-Foster J, Gehlenborg N, Gerken M, Getz G, Heiman D, Hobensack S, Holbrook A, Holt R, Hoyle A, Hutter C, Ittmann M, Jefferys S, Jones C, Jones S, Kasaian K, Kim J, Kimes P, Lai P, Laird P, Lawrence M, Lin P, Liu J, Lolla L, Lu Y, Ma Y, Maglinte D, Mallery D, Mardis E, Marra M, Martin J, Mayo M, Meier S, Meister M, Meng S, Meyerson M, Mieczkowski P, Miller C, Mills G, Moore R, Morris S, Mose L, Muley T, Mungall A, Mungall K, Naresh R, Newton Y, Noble M, Owonikoko T, Parker J, Paulaskis J, Penny R, Perou C, Perrin C, Pihl T, Radenbaugh A, Ramalingam S, Ramirez N, Rieker R, Roach J, Sadeghi S, Saksena G, Schein J, Schmidt H, Schumacher S, Shelton C, Shelton T, Shi Y, Shih J, Sica G, Silveira H, Simons J, Sipahimalani P, Skelly T, Sofia H, Soloway M, Stuart J, Sun Q, Tam A, Tan D, Tarnuzzer R, Thiessen N, Van Den Berg D, Vasef M, Veluvolu U, Voet D, Walter V, Wan Y, Wang Z, Warth A, Weis C, Weisenberger D, Wilkerson M, Wise L, Wong T, Wu H, Wu Y, Yang L, Zhang J, Zmuda E, Fujimoto J, Scapulatempo-Neto C, Moreira A, Hwang D, Huang J, Marino M, Korst R, Giaccone G, Gokmen-Polar Y, Badve S, Rajan A, Ströbel P, Girard N, Tsao M, Marx A, Tsao A, Loehrer P. The Integrated Genomic Landscape of Thymic Epithelial Tumors. Cancer Cell 2018, 33: 244-258.e10. PMID: 29438696, PMCID: PMC5994906, DOI: 10.1016/j.ccell.2018.01.003.Peer-Reviewed Original ResearchConceptsThymic epithelial tumorsEpithelial tumorsWorld Health Organization (WHO) histological subtypeAutoimmune disease myasthenia gravisDisease myasthenia gravisMuscle autoantigensThymic carcinomaMyasthenia gravisAutoimmune diseasesHistological subtypesAdult malignanciesTumoral overexpressionMarked prevalenceTumorsThymomaSubtypesEnrichment of mutationsGenomic landscapeBiological effectsGenomic hallmarksMolecular linkUnique associationAssociationMulti-platform analysisGravis
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