Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells
Yildirim O, Li R, Hung J, Chen P, Dong X, Ee L, Weng Z, Rando O, Fazzio T. Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells. Cell 2011, 147: 1498-1510. PMID: 22196727, PMCID: PMC3252821, DOI: 10.1016/j.cell.2011.11.054.Peer-Reviewed Original ResearchConceptsChromatin regulationEmbryonic stem (ES) cell self-renewalControl of gene expressionPromoter nucleosome occupancyPluripotent state of ES cellsES cellsMarked genesNucleosome occupancyCell Self-RenewalMBD3Gene expressionEmbryonic stem cellsBRG1GenesChromatinPluripotent stateSelf-RenewalRegulationCellsStem cellsExpressionRegulatory strategiesTET1KnockdownEffector
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