Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells
Blixt O, Lavrova O, Mazurov D, Cló E, Kračun S, Bovin N, Filatov A. Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells. Glycobiology 2011, 22: 529-542. PMID: 22143985, PMCID: PMC3287017, DOI: 10.1093/glycob/cwr178.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibodies, Monoclonal, Murine-DerivedAntibody SpecificityAntigens, CDAntigens, Tumor-Associated, CarbohydrateBinding, CompetitiveHumansImmunoglobulin GImmunoglobulin MJurkat CellsLeukemiaMembrane GlycoproteinsMiceMolecular ChaperonesMolecular Sequence DataMucin-1Peptide FragmentsProtein BindingRecombinant ProteinsConceptsAnti-Tn mAbsPeptide contextTn antigenTerminal GalNAc residueHuman Jurkat T cellsJurkat T cellsIgG mAbsChaperone CosmcAmino acid serineT-synthaseAnti-TnPeptide motifsGalNAc residuesPolypeptide chainO-glycoproteinsIsoforms of CD45Jurkat cellsLeukemia diagnosticsAnti-Tn monoclonal antibodyMonoclonal antibodiesBinding analysisIgM mAbAntigenic structureCarbohydrate moietyMotif
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