LUMATEPERONE TREATMENT FOR MAJOR DEPRESSIVE EPISODES WITH MIXED FEATURES IN MAJOR DEPRESSIVE DISORDER AND BIPOLAR I OR BIPOLAR II DISORDER
Bhagwagar *, Kozauer S, Earley W, Chen C, Huo J, Stahl S, McIntyre R, Durgam S. LUMATEPERONE TREATMENT FOR MAJOR DEPRESSIVE EPISODES WITH MIXED FEATURES IN MAJOR DEPRESSIVE DISORDER AND BIPOLAR I OR BIPOLAR II DISORDER. The International Journal Of Neuropsychopharmacology 2025, 28: i19-i19. PMCID: PMC11815047, DOI: 10.1093/ijnp/pyae059.033.Peer-Reviewed Original ResearchBipolar depressionBipolar II disorderII disorderLumateperone treatmentMDD populationBipolar IDSM-5Baseline to dayDSM-5-TRIncreased suicide riskMixing featuresPoor treatment responseAdverse eventsMADRS totalTreatment-emergent adverse eventsCGI-S scoresHypomanic symptomsDepressive disorderExtrapyramidal symptomsTreat schizophreniaDepressive episodeConsistent with prior studiesLumateperoneSuicide riskMDD
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