Cloning of a New "Finger" Protein Gene (ZNF173) within the Class I Region of the Human MHC
Chu T, Capossela A, Coleman R, Goei V, Nallur G, Gruen J. Cloning of a New "Finger" Protein Gene (ZNF173) within the Class I Region of the Human MHC. Genomics 1995, 29: 229-239. PMID: 8530076, DOI: 10.1006/geno.1995.1236.Peer-Reviewed Original ResearchMeSH Keywordsalpha-FetoproteinsAmino Acid SequenceAnimalsBase SequenceCloning, MolecularConsensus SequenceConserved SequenceDNA, ComplementaryDNA-Binding ProteinsGene LibraryGenes, MHC Class IHominidaeHumansKidneyMajor Histocompatibility ComplexMiceMolecular Sequence DataRestriction MappingSequence Homology, Amino AcidZinc FingersConceptsFull-length cDNA cloneClass I regionHuman coding regionsPartial genomic cloneHuman MHCConceptual proteinFinger proteinGenomic clonesPositional cloningCDNA clonesCDNA sequenceProtein genePolyglutamic acid regionCarboxyl terminusI regionBiological roleCoding regionsAcid regionRelated sequencesGenesMultiple tissuesProteinMajor histocompatability complexCloningNucleic acidsModulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand
Windhagen A, Schooz C, Höllsberg P, Fukaura H, Sette A, Hafler D. Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity 1995, 2: 373-380. PMID: 7536622, DOI: 10.1016/1074-7613(95)90145-0.Peer-Reviewed Original ResearchConceptsT cell clonesCytokine patternCell clonesHuman autoreactive T cell clonesT cell cytokine secretionAutoreactive T cell clonesT cell receptor contact residuesIL-4 secretionAltered peptide ligandMajor histocompatability complexPresence of ionomycinMyelin basic proteinIL-10Receptor contact residuesIL-4IL-2TCR antagonistsCytokine secretionImmune responseIFN-gammaPeptide ligandsProtein secretionCalcium fluxMature T-cell clonesSecretion
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