2024
Intermediate and long-term residual cardiovascular risk in patients with established cardiovascular disease treated with statins
Vijayaraghavan K, Baum S, Desai N, Voyce S. Intermediate and long-term residual cardiovascular risk in patients with established cardiovascular disease treated with statins. Frontiers In Cardiovascular Medicine 2024, 10: 1308173. PMID: 38288054, PMCID: PMC10822878, DOI: 10.3389/fcvm.2023.1308173.Peer-Reviewed Original ResearchLDL-CCV riskPeripheral arterial diseaseArtery diseaseCumulative incidence of CV eventsCV diseaseLowering of low-density lipoprotein cholesterolPatients treated with statinsIncidence of CV eventsLong-term event ratesWell-controlled LDL-CLow-density lipoprotein cholesterolLDL-C reductionAdd-on agentEvent ratesFirst-line treatmentResidual cardiovascular riskCV event ratesCoronary artery diseaseCV-related deathOmega-3 fatty acids eicosapentaenoic acidFirst-lineCumulative incidenceEicosapentaenoic acidCV events
2019
P6152Incremental prognostic utility of functionally non-significant coronary stenosis in patients undergoing coronary computed tomogram angiography
Alashi A, Huttcenteno E, Schoenhagen P, Popovic Z, Cremer P, Kalahasti V, Jellis C, Renapurkar R, Rodriguez L, Flamm S, Desai M. P6152Incremental prognostic utility of functionally non-significant coronary stenosis in patients undergoing coronary computed tomogram angiography. European Heart Journal 2019, 40: ehz746.0758. DOI: 10.1093/eurheartj/ehz746.0758.Peer-Reviewed Original ResearchHigh-risk plaque featuresCoronary artery diseasePlaque featuresModerate stenosisPrognostic utilityPrognostic valueNon-significant coronary artery diseaseHigh pre-test likelihoodMultivariable Cox survival analysisNon-significant coronary stenosisPrior coronary artery diseaseSevere coronary artery diseaseLong-term event ratesFractional flow reserve assessmentComposite of deathIncremental prognostic valueIntermediate-risk patientsMinimal luminal irregularitiesNonobstructive coronary plaqueLong-term freedomEpicardial coronary arteriesHistory of smokingPre-test likelihoodTraditional risk factorsIncremental prognostic utility226Earlier surgical myectomy vs. waiting for a Class I indication is associated with improved long-term survival in symptomatic hypertrophic obstructive cardiomyopathy patients
Alashi A, Smedira N, Hodges K, Popovic Z, Thamilarasan M, Wierup P, Lever H, Desai M. 226Earlier surgical myectomy vs. waiting for a Class I indication is associated with improved long-term survival in symptomatic hypertrophic obstructive cardiomyopathy patients. European Heart Journal 2019, 40: ehz747.0061. DOI: 10.1093/eurheartj/ehz747.0061.Peer-Reviewed Original ResearchClass I indicationsHypertrophic obstructive cardiomyopathySevere hypertrophic obstructive cardiomyopathySurgical myectomyHOCM patientsComposite endpointMedical therapySymptomatic hypertrophic obstructive cardiomyopathy patientsAppropriate internal defibrillator dischargeHypertrophic obstructive cardiomyopathy patientsVentricular outflow tract gradientImproved long-term survivalClass ILong-term event ratesBasal septal thicknessMaximal medical therapyOutflow tract gradientLong-term outcomesDeath risk scoreRisk survival analysisLong-term survivalExercise echoTract gradientExercise toleranceObstructive cardiomyopathy
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