Transcription factor BACH2 shapes tissue-resident memory T cell programs to promote HIV-1 persistence
Wei Y, Katherine H, Wong M, Back H, Papasavvas E, Mounzer K, Aberra F, Morgenstern R, Tebas P, Konnikova L, Montaner L, Ho Y. Transcription factor BACH2 shapes tissue-resident memory T cell programs to promote HIV-1 persistence. Immunity 2025 DOI: 10.1016/j.immuni.2025.07.022.Peer-Reviewed Original ResearchCD8+ T cellsHIV-1 persistenceT cell receptorT cellsHIV-1Tissue residencyHIV-1-specific CD8+ T cellsLong-lived memoryEffector functionsTissue-resident memory T cellsHIV-1 immune evasionHIV-1-infected cellsHIV-1 DNAMemory T cellsHIV-1 RNAT cell programmingEffector memoryHIV- donorsCD4+Immune evasionMucosal immunityIn vitroSurface proteinsChromatin accessibilityTranscription factors
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