2023
PO83 Utilization of a Virtual Clinical Trial to Characterize Sensitivity of the Linear-Quadratic Model
Tien C, Draeger E, Guan F, Carlson D, Chen Z. PO83 Utilization of a Virtual Clinical Trial to Characterize Sensitivity of the Linear-Quadratic Model. Brachytherapy 2023, 22: s110. DOI: 10.1016/j.brachy.2023.06.184.Peer-Reviewed Original ResearchTumor control probabilityClinical trialsLinear-quadratic modelNumber of patientsPatient cohort sizeTCP curvesRadiobiological parametersVirtual clinical trialsGy-1Cohort sizeRange of dosesPatient outcomesReference cohortPatientsHeterogeneous cohortVirtual patientsNew trialsRadiobiological parameter valuesClonogenic populationPatient ordersControl probabilityGyInput model parametersTrialsCohort
2015
High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients
Shuryak I, Carlson DJ, Brown JM, Brenner DJ. High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients. Radiotherapy And Oncology 2015, 115: 327-334. PMID: 26058991, DOI: 10.1016/j.radonc.2015.05.013.Peer-Reviewed Original ResearchConceptsMulti-fraction stereotactic radiotherapyStereotactic radiotherapyTumoricidal mechanismsTumor controlHigh dosesSingle-dose stereotactic radiotherapySingle-fraction treatmentStereotactic radiation therapyTumor control dataBrain metastasesLung tumorsSRT patientsRadiation therapyTreatment dosesLow dosesSRT treatmentDosesLinear-quadratic modelPatientsFraction numberTreatmentLung dataLQ modelControl dataMetastasis
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