2023
LI-RADS: Looking Back, Looking Forward.
Chernyak V, Fowler K, Do R, Kamaya A, Kono Y, Tang A, Mitchell D, Weinreb J, Santillan C, Sirlin C. LI-RADS: Looking Back, Looking Forward. Radiology 2023, 307: e222801. PMID: 36853182, PMCID: PMC10068888, DOI: 10.1148/radiol.222801.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaLI-RADSSensitivity of LR-5Imaging modalitiesRadiation-based therapyTreatment response assessmentLiver Imaging ReportingLiver imaging modalityQuantitative imaging featuresExtracellular contrast agentsContrast agentsLR-5Systemic treatmentResponse assessmentImaging ReportingPatient characteristicsLiver cancerIndeterminate observationsClinical careDiagnosisLiverModalitiesReporting templateTreatmentImage features
2021
Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization.
Consul N, Sirlin CB, Chernyak V, Fetzer DT, Masch WR, Arora SS, Do RKG, Marks RM, Fowler KJ, Borhani AA, Elsayes KM. Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization. RadioGraphics 2021, 41: 1657-1675. PMID: 34559586, DOI: 10.1148/rg.2021210019.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaEnhancement patternLiver observationsCapsule appearanceRim arterial phase hyperenhancementAncillary featuresNon-HCC malignanciesLocal-regional therapyArterial phase hyperenhancementLiver Imaging ReportingDynamic contrast-enhanced imagingDifferent enhancement patternsImaging-based diagnosisContrast-enhanced imagingPeripheral washoutArterioportal shuntTargetoid appearanceNodular enhancementCorona enhancementBenign entityTreatment responseLI-RADSRisk populationsLiver lesionsSpecific diagnosis
2020
Hepatocellular carcinoma Liver Imaging Reporting and Data Systems treatment response assessment: Lessons learned and future directions
Aslam A, Gian R, Kambadakone A, Spieler B, Miller FH, Gabr AM, Charalel RA, Kim CY, Madoff DC, Mendiratta-Lala M. Hepatocellular carcinoma Liver Imaging Reporting and Data Systems treatment response assessment: Lessons learned and future directions. World Journal Of Hepatology 2020, 12: 738-753. PMID: 33200013, PMCID: PMC7643220, DOI: 10.4254/wjh.v12.i10.738.Peer-Reviewed Original ResearchTreatment response algorithmLI-RADS treatment response algorithmLocoregional therapyLiver Imaging ReportingHepatocellular carcinomaTreatment response assessmentTreatment optionsResponse assessmentData System treatment response algorithmImaging ReportingDifferent locoregional therapiesLiver transplant candidacyHCC treatment responseTransplant candidacyOverall survivalSystemic therapyTumor burdenLeading causeTreatment responseLI-RADSTumor assessmentEconomic burdenClinical practiceTumor progressionTherapy
2018
Validation of Liver Imaging Reporting and Data System 2017 (LI‐RADS) Criteria for Imaging Diagnosis of Hepatocellular Carcinoma
Kierans AS, Makkar J, Guniganti P, Cornman‐Homonoff J, Lee MJ, Pittman M, Askin G, Hecht EM. Validation of Liver Imaging Reporting and Data System 2017 (LI‐RADS) Criteria for Imaging Diagnosis of Hepatocellular Carcinoma. Journal Of Magnetic Resonance Imaging 2018, 49: e205-e215. PMID: 30257054, DOI: 10.1002/jmri.26329.Peer-Reviewed Original ResearchConceptsLiver Imaging ReportingHepatocellular carcinomaLI-RADSInterreader reliabilityDiagnostic performanceFurther large-scale prospective studiesFrequency of HCCImaging ReportingLarge-scale prospective studiesAncillary featuresLI-RADS categorizationLiver transplant candidatesStage 3 J. MagnLI-RADS categoryMulticenter validation studyPositive predictive valueDiffusion-weighted imagingTransplant candidatesProspective studyExtracellular agentsSpecificity 85.0Clinical practicePredictive valueLiver MRIImaging diagnosisWhite paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI
Elsayes KM, Kielar AZ, Elmohr MM, Chernyak V, Masch WR, Furlan A, Marks RM, Cruite I, Fowler KJ, Tang A, Bashir MR, Hecht EM, Kamaya A, Jambhekar K, Kamath A, Arora S, Bijan B, Ash R, Kassam Z, Chaudhry H, McGahan JP, Yacoub JH, McInnes M, Fung AW, Shanbhogue K, Lee J, Deshmukh S, Horvat N, Mitchell DG, Do RKG, Surabhi VR, Szklaruk J, Sirlin CB. White paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI. Abdominal Radiology 2018, 43: 2625-2642. PMID: 30155697, DOI: 10.1007/s00261-018-1744-4.Peer-Reviewed Original ResearchConceptsLI-RADS v2018Hepatocellular carcinomaClinical practice guidanceDiagnostic imaging criteriaImaging-based diagnosisReporting Data SystemSurveillance ultrasoundLiver diseaseImaging criteriaArterial phaseLI-RADSClinical careOrgan procurementLiver imagingDiagnostic algorithmV2018American AssociationPractice guidanceThreshold growthNetwork definitionAASLDPatientsCarcinomaData System
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