2018
Oncolytic virus immunotherapy: future prospects for oncology
Raja J, Ludwig JM, Gettinger SN, Schalper KA, Kim HS. Oncolytic virus immunotherapy: future prospects for oncology. Journal For ImmunoTherapy Of Cancer 2018, 6: 140. PMID: 30514385, PMCID: PMC6280382, DOI: 10.1186/s40425-018-0458-z.Peer-Reviewed Original ResearchConceptsOncolytic virusesSevere immune-related adverse eventsImmune-related adverse eventsAnti-tumor immune responseEarly-stage clinical trialsImmune checkpoint inhibitorsSerious adverse effectsOncolytic viral therapyLimited therapeutic responseAnti-cancer treatmentLocal target cellsCheckpoint inhibitorsSalvage therapyTolerability profileCytotoxic chemotherapyAdverse eventsImmune dysregulationOncologic careTherapeutic optionsTumor bedSuch therapyTherapeutic responseClinical trialsNovel therapiesViral therapy
2003
Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice.
Onn A, Isobe T, Itasaka S, Wu W, O'Reilly MS, Ki Hong W, Fidler IJ, Herbst RS. Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice. Clinical Cancer Research 2003, 9: 5532-9. PMID: 14654533.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarcinoma, Non-Small-Cell LungCarcinoma, Small CellCarcinoma, Squamous CellCell Line, TumorFibroblast Growth Factor 2HumansInterleukin-8Lung NeoplasmsLymphatic MetastasisMiceMice, NudeModels, BiologicalNeoplasm MetastasisNeovascularization, PathologicPaclitaxelVascular Endothelial Growth Factor AConceptsNon-small cell lung cancerHuman lung cancerCell lung cancerLung cancerOrthotopic modelNude miceHuman primary lung cancerPrimary human lung cancersSmall cell lung cancer cellsExtrathoracic lymph nodesCell lung cancer cellsPrimary lung cancerSquamous cell carcinomaLung cancer cell linesLung cancer biologyVascular endothelial growth factor/vascular permeability factorLimited therapeutic responseRelevant animal modelsNovel therapeutic strategiesBasic fibroblast growth factorCell lung cancer biologyHuman lung adenocarcinomaLung cancer cellsLung cancer tumorsVascular permeability factor
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