Subnormothermic Regulated Hepatic Reperfusion Preserves Mitochondrial Function in Swine Liver Procured after Cardiac Death
Stowe D, Yang M, Mishra J, Kim J, Heisner J, Zimmerman M, Camara A, Hong J. Subnormothermic Regulated Hepatic Reperfusion Preserves Mitochondrial Function in Swine Liver Procured after Cardiac Death. The FASEB Journal 2018, 32: lb161-lb161. DOI: 10.1096/fasebj.2018.32.1_supplement.lb161.Peer-Reviewed Original ResearchIschemia-reperfusion injuryIn situ warm ischemiaMitochondrial functionSubstrate succinateLiver transplantationHepatic reperfusionCardiac deathRespiratory control indexCapability of mitochondriaIncreased risk of graft failureWarm ischemiaRisk of graft failureDegree of ischemia-reperfusion injuryMeasuring mitochondrial bioenergeticsPreservation of mitochondrial functionState 4 respiration ratesIsolated mitochondriaEx vivo reperfusionHuman liver transplantationProton leakMitochondrial bioenergeticsMarkers of mitochondrial dysfunctionMitochondrial dysfunctionMitochondrial recoveryLeukocyte-depleted
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