2014
Working memory and reward association learning impairments in obesity
Coppin G, Nolan-Poupart S, Jones-Gotman M, Small DM. Working memory and reward association learning impairments in obesity. Neuropsychologia 2014, 65: 146-155. PMID: 25447070, PMCID: PMC4259845, DOI: 10.1016/j.neuropsychologia.2014.10.004.Peer-Reviewed Original ResearchConceptsHealthy weight individualsNegative outcomesExplicit learningReward association learningProbabilistic learning taskFunction of groupHealthy weight groupObese individualsReward associationsStimulus-rewardExecutive functionAssociation learningLearning taskExperiment 1Learning impairmentHealthy weightParadoxical preferenceWeight individualsPositive outcomesMemoryWeight groupInfluence of obesitySecond experimentCurrent studyDeficits
2011
Mutation of the dyslexia‐associated gene Dcdc2 impairs LTM and visuo‐spatial performance in mice
Gabel L, Marin I, LoTurco J, Che A, Murphy C, Manglani M, Kass S. Mutation of the dyslexia‐associated gene Dcdc2 impairs LTM and visuo‐spatial performance in mice. Genes Brain & Behavior 2011, 10: 868-875. PMID: 21883923, PMCID: PMC3212622, DOI: 10.1111/j.1601-183x.2011.00727.x.Peer-Reviewed Original ResearchConceptsReading disordersMemory deficitsDCDC2 mutationsVisuo-spatial memory deficitsLong-term memory deficitsDevelopmental reading disordersVisuo-spatial learningVisuo-spatial performanceAnxiety phenotypeMemory taskLearning impairmentBehavioral deficitsBehavioral measuresNeural mechanismsCognitive abilitiesMutant miceVisual discriminationVisual attentionSchool age childrenDCDC2DeficitsAge childrenGenetic association studiesHomozygous mutationADHD
1983
Differential effects of selective dopamine, norepinephrine or catecholamine depletion on activity and learning in the developing rat
Raskin L, Shaywitz B, Anderson G, Cohen D, Teicher M, Linakis J. Differential effects of selective dopamine, norepinephrine or catecholamine depletion on activity and learning in the developing rat. Pharmacology Biochemistry And Behavior 1983, 19: 743-749. PMID: 6647508, DOI: 10.1016/0091-3057(83)90073-4.Peer-Reviewed Original ResearchConceptsDays of ageT-mazeCentral catecholamine systemsSelective dopamine depletionSelective norepinephrine depletionDopamine depletionNE levelsNorepinephrine depletionCatecholamine depletionSevere learning impairmentIntraperitoneal injectionCatecholamine systemsSelective lesionsDay 28Selective dopamineNeonatal depletionLearning impairmentSelective depletionCatecholaminesClinical researchBehavioral effectsDeficit disorderShuttlebox performanceActivity levelsConstellation of behaviors
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