2020
Genetic Study in Korean Pediatric Patients with Steroid-Resistant Nephrotic Syndrome or Focal Segmental Glomerulosclerosis
Park E, Lee C, Kim N, Ahn Y, Park Y, Lee J, Kim S, Cho M, Cho H, Yoo K, Shin J, Kang H, Ha I, Park W, Cheong H. Genetic Study in Korean Pediatric Patients with Steroid-Resistant Nephrotic Syndrome or Focal Segmental Glomerulosclerosis. Journal Of Clinical Medicine 2020, 9: 2013. PMID: 32604935, PMCID: PMC7355646, DOI: 10.3390/jcm9062013.Peer-Reviewed Original ResearchSteroid-resistant nephrotic syndromeMutation detection rateFocal segmental glomerulosclerosisKorean pediatric patientsEnd-stage renal diseasePediatric patientsNephrotic syndromeSegmental glomerulosclerosisGenotype-phenotype correlation studiesAssociated with focal segmental glomerulosclerosisPrediction of prognosisGenotype-phenotype correlationDetection rateSteroid treatmentCongenital onsetStudy cohortRenal diseaseGenetic studiesGenetic diagnosisCausative genesMonogenic causePatientsTreatment policyMutationsCohort
2014
Efficacy and Safety of Rituximab in Children with Refractory Nephrotic Syndrome; A Multicenter Clinical Trial
Ahn Y, Kang H, Kim S, Han K, Cho H, Shin J, Cho M, Park Y, Kim S, Lee S, Cheong H, Ha I. Efficacy and Safety of Rituximab in Children with Refractory Nephrotic Syndrome; A Multicenter Clinical Trial. Kidney Research And Clinical Practice 2014, 33: a1-a2. DOI: 10.1016/j.krcp.2014.05.017.Peer-Reviewed Original ResearchSafety of RTXStandard therapy armRefractory nephrotic syndromeRefractory NSCalcineurin inhibitorsNephrotic syndromeClinical trialsRTX treatmentTherapy armSolid evidence of efficacyAnti-CD20 Monoclonal AntibodyMulticenter open-label trialLong-term safety profileCD19 cell countsSafety of rituximabKorean pediatric patientsMaintenance of remissionPrimary end pointOpen-label trialRandomized to standard treatmentSingle-arm studyMulticenter clinical trialRandomized clinical trialsEvidence of efficacyRTX administration
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