2020
Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants
Landim-Vieira M, Johnston JR, Ji W, Mis EK, Tijerino J, Spencer-Manzon M, Jeffries L, Hall EK, Panisello-Manterola D, Khokha MK, Deniz E, Chase PB, Lakhani SA, Pinto JR. Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants. Frontiers In Physiology 2020, 10: 1612. PMID: 32038292, PMCID: PMC6990120, DOI: 10.3389/fphys.2019.01612.Peer-Reviewed Original ResearchCardiac muscle preparationsIsometric forcePatient variantsEarly-onset DCMDilated Cardiomyopathy AssociatedCompound heterozygous variantsSteady-state isometric forceCardiomyopathy AssociatedContractile functionMuscle preparationsCardiomyopathy phenotypeHeterozygous variantsCardiac phenotypeMyofilament CaSarcomeric genesFurther studies
2000
Time and dose effect of transdermal nicotine on endothelial function
Miller V, Clouse W, Tonnessen B, Boston U, Severson S, Bonde S, Rud K, Hurt R. Time and dose effect of transdermal nicotine on endothelial function. AJP Heart And Circulatory Physiology 2000, 279: h1913-h1921. PMID: 11009480, DOI: 10.1152/ajpheart.2000.279.4.h1913.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine DiphosphateAdministration, CutaneousAnimalsAortaCalcimycinCalciumCoronary VesselsCotinineDogsDose-Response Relationship, DrugEndothelium, VascularEnzyme InhibitorsIn Vitro TechniquesIonophoresMaleNicotineNitratesNitric Oxide SynthaseNitritesomega-N-MethylarginineRNA, MessengerTime FactorsVasodilationConceptsEndothelium-dependent responsesEndothelium-dependent relaxationNicotine patchNicotine treatmentNitric oxideNicotine patch therapyEffects of nicotineBiphasic dose effectDose effectCalcium ionophore AAortic endothelial cellsTransdermal nicotineEndothelial functionPatch therapyCoronary arteryCounter medicationsCessation programsNOS activityAdrenergic agonistsNOS mRNAIonophore AIsometric forceEndothelial cellsNicotineDose range
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