2024
Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial Transcriptomics
Mohanty C, Singh C, Daccache J, Damsky W, Kendziorski C, Yan D, Prasad A, Zhang D, Keenan T, Drolet B, Ahmad N, Shields B. Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial Transcriptomics. Journal Of Investigative Dermatology 2024, 145: 109-121. PMID: 38844128, DOI: 10.1016/j.jid.2024.04.024.Peer-Reviewed Original ResearchGranuloma annulareGranulomatous inflammationFDA-approved therapiesInflammatory signaling cascadesImpact of GAIFN-gImmune cellsInterleukin-32Idiopathic conditionTh2 signalsAdaptive immunityInterstitial patternMacrophage activationGene expression changesMolecular driversQuality of lifeGenome-wide gene expression changesMacrophage polarizationGranulomaMacrophagesTissue remodelingInflammationTNF signalingLocal gene expression patternsSpatial transcriptomics
1997
Evaluation of Classic Architectural Criteria in Non-mycosis Fungoides Cutaneous Lymphomas
Glusac E, Kindel S, Soslow R, Smoller B. Evaluation of Classic Architectural Criteria in Non-mycosis Fungoides Cutaneous Lymphomas. American Journal Of Dermatopathology 1997, 19: 557-561. PMID: 9415610, DOI: 10.1097/00000372-199712000-00001.Peer-Reviewed Original ResearchConceptsT-cell lymphomaB-cell patternB-cell lymphomaLarge cell lymphomaCutaneous lymphomasGrenz zoneSecondary cutaneous B-cell lymphomasRare B-cell lymphomaCutaneous B-cell lymphomaPresence of epidermotropismT cell patternMost B-cell lymphomasDense perivascularCutaneous malignanciesPrevious diagnosisInterstitial patternHistologic patternHistologic criteriaImmunohistochemical studyDeep dermisLymphomaUpper dermisNodular collectionsIndeterminate patternEpidermotropism
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