2023
Magnetic resonance imaging using a nonuniform Bo (NuBo) field-cycling magnet
Selvaganesan K, Wan Y, Ha Y, Wu B, Hancock K, Galiana G, Constable R. Magnetic resonance imaging using a nonuniform Bo (NuBo) field-cycling magnet. PLOS ONE 2023, 18: e0287344. PMID: 37319289, PMCID: PMC10270621, DOI: 10.1371/journal.pone.0287344.Peer-Reviewed Original ResearchConceptsInnovative data acquisitionMain magnetGradient coilsExperimental verificationEcho signalsInitial designField cyclingParallel imagingSuperior soft tissue contrastMagnetsInhomogeneous fieldsLow fieldsSoft tissue contrastReconstruction approachInhomogeneity effectsData acquisitionSpatial encodingPolarization phaseOpen MR systemPowerful noninvasive diagnostic toolSpin echo signalImage acquisitionFieldCoilNew approach
2003
X-ray Structure of a Maquette Scaffold
Huang S, Gibney B, Stayrook S, Dutton P, Lewis M. X-ray Structure of a Maquette Scaffold. Journal Of Molecular Biology 2003, 326: 1219-1225. PMID: 12589764, DOI: 10.1016/s0022-2836(02)01441-9.Peer-Reviewed Original ResearchConceptsLeft-handed coiled-coilsCoiled-coilAnti-parallel four-helix bundleHeptad repeat patternFour-alpha-helical bundleMaquette scaffoldFour-helix bundleHeme-binding propertiesX-ray structureMAD phasingHeme binding pocketIdentical helicesResidue positionsHeptad repeatHydrophobic residuesPacking interfaceProtein scaffoldEngineering criteriaHeptadMaquettesRepeat patternHelixDesign criteriaX-rayInitial design
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