2021
Microinjection of Xenopus tropicalis Embryos.
Lane M, Mis EK, Khokha MK. Microinjection of Xenopus tropicalis Embryos. Cold Spring Harbor Protocols 2021, 2022: pdb.prot107644. PMID: 34244348, DOI: 10.1101/pdb.prot107644.Peer-Reviewed Original ResearchConceptsEmbryo sizeLarger embryo sizeTargeted gene manipulationEmbryo development timeSmall embryo sizeXenopus tropicalis embryosDevelopmental biologyEarly embryosMicroinjection protocolGene manipulationGenetic studiesFirst divisionXenopusEmbryosImportant modelDevelopment timeMicroinjectionMorpholinoCRISPRBiologySpeciesDNAMRNAOocytesFertilization
2016
Reconstructing Causal Biological Networks through Active Learning
Cho H, Berger B, Peng J. Reconstructing Causal Biological Networks through Active Learning. PLOS ONE 2016, 11: e0150611. PMID: 26930205, PMCID: PMC4773135, DOI: 10.1371/journal.pone.0150611.Peer-Reviewed Original ResearchConceptsGaussian Bayesian networksBayesian networkContinuous Bayesian networksDiscrete Bayesian networksBiological networksFast convergenceGreat practical interestGene regulatory networksGraph structurePractical interestQuantitative propertiesSignificant runtime improvementsComplex biological systemsRuntime improvementCausal biological networksSystems biologyCentral problemFinal distributionPrevious approachesNetwork structureResource constraintsData setsLearning algorithmImportant modelActive learning algorithm
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