A Systematic Review of Conversion to Resectability in Unresectable Metastatic Colorectal Cancer Chemotherapy Trials
Chrabaszcz S, Rajeev R, Witmer H, Dhiman A, Klooster B, Gamblin T, Banerjee A, Johnston F, Turaga K. A Systematic Review of Conversion to Resectability in Unresectable Metastatic Colorectal Cancer Chemotherapy Trials. American Journal Of Clinical Oncology 2022, 45: 366-372. PMID: 35838247, DOI: 10.1097/coc.0000000000000921.Peer-Reviewed Original ResearchConceptsMetastatic colorectal cancerUnresectable metastatic colorectal cancerOverall survivalClinical trialsPrimary outcome of OSStudy armsImproved OS of patientsConversion to resectabilitySuperior overall survivalOS of patientsSignificant survival benefitOutcomes of OSMedian survival differenceRandomized clinical trialsHigh response rateDose-effect responseMedian OSImproved OSChemotherapy trialsSurvival benefitExposure of interestPatient cohortSurvival differencesChemotherapeutic agentsColorectal cancer
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