A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture
Morales-Navarrete H, Segovia-Miranda F, Klukowski P, Meyer K, Nonaka H, Marsico G, Chernykh M, Kalaidzidis A, Zerial M, Kalaidzidis Y. A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture. ELife 2015, 4: e11214. PMID: 26673893, PMCID: PMC4764584, DOI: 10.7554/elife.11214.Peer-Reviewed Original ResearchConceptsSystems biology analysisHigh-throughput analysisMulti-scale reconstructionCell shapeTissue architectureDigital three-dimensional reconstructionMammalian tissuesZonation patternsLiver cell typesCell typesDNA contentTissue organizationParameters of sinusoidsImages of markersFlexible workflowAnalysis of tissuesQuantitative morphological analysisAnalysis of liver tissueMorphological analysisFlexible pipelineArchitectureDNAKidney tissueTissueBile canaliculi
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