2007
The Control of Transmembrane Helix Transverse Position in Membranes by Hydrophilic Residues
Krishnakumar SS, London E. The Control of Transmembrane Helix Transverse Position in Membranes by Hydrophilic Residues. Journal Of Molecular Biology 2007, 374: 1251-1269. PMID: 17997412, PMCID: PMC2175128, DOI: 10.1016/j.jmb.2007.10.032.Peer-Reviewed Original Research
2000
A family of genes with growth factor and adenosine deaminase similarity are preferentially expressed in the salivary glands of Glossina m. morsitans
Li S, Aksoy S. A family of genes with growth factor and adenosine deaminase similarity are preferentially expressed in the salivary glands of Glossina m. morsitans. Gene 2000, 252: 83-93. PMID: 10903440, DOI: 10.1016/s0378-1119(00)00226-2.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine DeaminaseAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernBlotting, SouthernDNADNA, ComplementaryFemaleGene Expression RegulationGene Expression Regulation, DevelopmentalGrowth SubstancesMaleMolecular Sequence DataRNA, MessengerSalivaSalivary GlandsSequence Analysis, DNASpecies SpecificityTissue DistributionTsetse FliesConceptsOpen reading frameFemale adult fliesDeduced protein sequenceSignal peptide characteristicDifferent fly tissuesFamily of genesFull-length cDNAAmino acid identityLarval developmental stagesRegulation of expressionN-terminal regionGrowth factorAmino acid residuesTissues of adultAnalysis of proteinsGenomic arrangementPutative proteinFly tissuesSarcophaga peregrinaAcid identityHydrophobic sequenceCDNA libraryReading frameAdult fliesProtein sequences
1997
Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix †
Hunt J, Rath P, Rothschild K, Engelman D. Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix †. Biochemistry 1997, 36: 15177-15192. PMID: 9398245, DOI: 10.1021/bi970147b.Peer-Reviewed Original ResearchConceptsLipid bilayersIntegral membrane protein bacteriorhodopsinMembrane-spanning regionIntegral membrane proteinsPH-dependent membrane insertionAspartic acid residuesMembrane protein bacteriorhodopsinInsertion reactionMembrane insertionMembrane proteinsAqueous solutionHydrophobic sequenceAqueous bufferPoor solubilityAlpha-helixAcid residuesSignificant solubilityC-helixSpectroscopic assaysΑ-helixSecondary structureProtein bacteriorhodopsinNeutral pHPeptide associatesBilayers
1992
The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamine
Kulke R, Horwitz B, Zibello T, DiMaio D. The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamine. Journal Of Virology 1992, 66: 505-511. PMID: 1727496, PMCID: PMC238311, DOI: 10.1128/jvi.66.1.505-511.1992.Peer-Reviewed Original ResearchConceptsHydrophobic amino acidsAmino acidsE5 proteinRandom hydrophobic sequencesHydrophobic domainRodent fibroblast cell linesCentral hydrophobic domainHydrophobic amino acid sequenceCarboxyl-terminal amino acidsMouse C127 cellsAmino acid sequenceClasses of mutantsAbsence of glutamineBovine papillomavirus E5Mutant proteinsTransforming proteinDefective mutantsHydrophobic sequenceFibroblast cell lineProtein stabilityAcid sequenceC127 cellsHomodimer formationEfficient transformationProtein
1989
Transforming activity of a 16-amino-acid segment of the bovine papillomavirus E5 protein linked to random sequences of hydrophobic amino acids
Horwitz B, Weinstat D, DiMaio D. Transforming activity of a 16-amino-acid segment of the bovine papillomavirus E5 protein linked to random sequences of hydrophobic amino acids. Journal Of Virology 1989, 63: 4515-4519. PMID: 2552136, PMCID: PMC251082, DOI: 10.1128/jvi.63.11.4515-4519.1989.Peer-Reviewed Original ResearchConceptsE5 proteinAmino acidsWild-type E5 proteinBovine papillomavirus E5 proteinAmino acid sequence requirementsHydrophobic amino acid sequenceCarboxyl-terminal amino acidsMouse C127 cellsAmino acid sequenceBovine papillomavirus type 1Carboxyl-terminal portionWild-type onesHydrophobic amino acidsPapillomavirus type 1Hydrophobic sequenceDifferent amino acidsAcid sequenceC127 cellsSequence requirementsE5 geneCell transformationFoci formationSubstitution mutationsCell membraneProtein
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