Gene Editing in Human Lymphoid Cells: Role for Donor DNA, Type of Genomic Nuclease and Cell Selection Method
Zotova A, Lopatukhina E, Filatov A, Khaitov M, Mazurov D. Gene Editing in Human Lymphoid Cells: Role for Donor DNA, Type of Genomic Nuclease and Cell Selection Method. Viruses 2017, 9: 325. PMID: 29099045, PMCID: PMC5707532, DOI: 10.3390/v9110325.Peer-Reviewed Original ResearchConceptsAdeno-associated virus integration site 1Virus type 1Lymphoid cellsHuman lymphoid cellsNon-Homologous End JoiningZinc finger nucleasesHIV-1Human immunodeficiency virus type 1Immunodeficiency virus type 1Type 1Replication of HIV-1Virus integration site 1Human T-cell leukemia virus type 1B cell linesDifficult-to-transfect cellsGene function validationHTLV-1Human TOn-target efficiencyCEM cellsOff-target effectsTarget lociGene-edited cellsHomologous recombinationOn-target activity
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