Single-Cell Transcriptomic Analyses of Cell Fate Transitions during Human Cardiac Reprogramming
Zhou Y, Liu Z, Welch J, Gao X, Wang L, Garbutt T, Keepers B, Ma H, Prins J, Shen W, Liu J, Qian L. Single-Cell Transcriptomic Analyses of Cell Fate Transitions during Human Cardiac Reprogramming. Cell Stem Cell 2019, 25: 149-164.e9. PMID: 31230860, PMCID: PMC6684137, DOI: 10.1016/j.stem.2019.05.020.Peer-Reviewed Original ResearchConceptsCell fate transitionsCell fate determinationSingle-cell transcriptomic studiesCell fate conversionFate transitionsSingle-cell transcriptome analysisReprogramming progressionFate determinationDNA methylationFunctional screeningFate conversionCellular reprogrammingDownstream targetsAnalysis pipelineAnalytical pipelineFibroblast stateReprogrammingCell plasticityReprogramming factorsMolecular featuresCellsHuman cardiacTrajectory prediction algorithmPrediction algorithmFibroblasts
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