Genomic characterization of small cell carcinomas of the uterine cervix
Schultheis A, de Bruijn I, Selenica P, Macedo G, da Silva E, Piscuoglio S, Jungbluth A, Park K, Klimstra D, Wardelmann E, Hartmann W, Gerharz C, von Petersdorff M, Buettner R, Reis‐Filho J, Weigelt B. Genomic characterization of small cell carcinomas of the uterine cervix. Molecular Oncology 2021, 16: 833-845. PMID: 33830625, PMCID: PMC8847983, DOI: 10.1002/1878-0261.12962.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerSmall cell carcinomaSquamous cell carcinomaUterine cervixCell carcinomaHuman papillomavirus (HPV)-positive headHead and neck squamous cell carcinomaHPV-positive cervical carcinomasNeck squamous cell carcinomaHPV-driven cancersLow mutational burdenTargeted massively parallel sequencingHPV-positive headCell lung cancerCopy number alterationsCombination of whole-exomePoor survival rateAPOBEC mutational signaturesCancer-related genesMassively parallel sequencingNeuroendocrine carcinomaRB1 alterationsHPV16-positiveMutational burdenRB1 mutations
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