2021
Venetoclax and Azacitidine in the Treatment of Patients with Relapsed/Refractory Myelodysplastic Syndrome
Zeidan A, Borate U, Pollyea D, Brunner A, Roncolato F, Garcia J, Filshie R, Odenike O, Watson A, Krishnadasan R, Bajel A, Naqvi K, Zha J, Hogdal L, Zhou Y, Hoffman D, Kye S, Garcia-Manero G. Venetoclax and Azacitidine in the Treatment of Patients with Relapsed/Refractory Myelodysplastic Syndrome. Blood 2021, 138: 537. DOI: 10.1182/blood-2021-145646.Peer-Reviewed Original ResearchClinical Trials CommitteeHigh-risk myelodysplastic syndromeMedian overall survivalAdverse eventsMyelodysplastic syndromeTrials CommitteeOverall survivalMedian timeClinical trialsFebrile neutropeniaPrior therapyComplete remissionTransfusion independenceClinical outcomesBcl-2 inhibitorsMyeloid leukemiaEastern Cooperative Oncology Group performance statusGrade treatment-emergent adverse eventsInternational Working Group 2006 criteriaOverall median progression-free survivalIncomplete blood count recoveryMedian progression-free survivalOral BCL-2 inhibitorTreatment-emergent adverse eventsAllogeneic hematopoietic stem cells
2008
Outcomes in Subcutaneous Panniculitis-Like T-Cell Lymphoma (STCL)
Alpdogan O, Ornstein D, Subtil T, Seropian S, Cooper D, Foss F. Outcomes in Subcutaneous Panniculitis-Like T-Cell Lymphoma (STCL). Blood 2008, 112: 3750. DOI: 10.1182/blood.v112.11.3750.3750.Peer-Reviewed Original ResearchSubcutaneous panniculitis-like T-cell lymphomaPanniculitis-like T-cell lymphomaTCR gene rearrangementsT-cell lymphomaRetrospective studyDenileukin diftitoxPoor prognosisT cellsCytotoxic T-cell markersAllogeneic hematopoietic stem cellsT cell receptor expressionCytotoxic chemotherapy regimensMatched-related donorsEvidence of diseaseRare clinical entityAggressive clinical courseT-cell markersMalignant T cellsCell receptor expressionClonal TCR gene rearrangementNovel T cellAllogeneic HSCTMedian followAggressive therapyChemotherapy regimens
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