Metrics Derived from Architecture of Tumor-Infiltrating Lymphocytes are Associated with Overall Survival in HPV-Positive Oropharyngeal Squamous Cell Carcinoma Patients: Results from NRG/RTOG 0129 and 0522
Corredor G, Harris J, Koyuncu C, Pathak T, Pandav K, Toro P, Yang K, Faraji F, Castro P, Sandulache V, Koyfman S, Nguyen F, Garden A, Caudell J, Jones C, Rosenthal D, Le Q, Lewis J, Madabhushi A. Metrics Derived from Architecture of Tumor-Infiltrating Lymphocytes are Associated with Overall Survival in HPV-Positive Oropharyngeal Squamous Cell Carcinoma Patients: Results from NRG/RTOG 0129 and 0522. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: s130. DOI: 10.1016/j.ijrobp.2024.07.236.Peer-Reviewed Original ResearchTumor-infiltrating lymphocytesDisease-free survivalOverall survivalHazard ratioHPV+ OPSCCPoor survivalRisk of disease-free survivalOropharyngeal squamous cell carcinoma patientsDisease-free survival modelsSquamous cell carcinoma patientsTreated with standard therapyRisk of overall survivalAssociated with overall survivalHigh-risk ptsRisk scoreCell carcinoma patientsRisk of poor survivalSubsets of patientsCox regression modelsLow-risk counterpartsHPV-PositivePrimary tumorCarcinoma patientsStandard therapyInstitutional cohort1895-LB: Fasting C-Peptide and Type 1 Diabetes Polygenic Score Predict Diabetic Ketoacidosis in People with Type 2 Diabetes in DECLARE-TIMI 58
MI KANG Y, MELLONI G, CAHN A, RAZ I, MOURA F, BHATT D, INZUCCHI S, LEITER L, MCGUIRE D, WILDING J, GAUSE-NILSSON I, OSCARSSON J, MARSTON N, RUFF C, SABATINE M, WIVIOTT S. 1895-LB: Fasting C-Peptide and Type 1 Diabetes Polygenic Score Predict Diabetic Ketoacidosis in People with Type 2 Diabetes in DECLARE-TIMI 58. Diabetes 2024, 73 DOI: 10.2337/db24-1895-lb.Peer-Reviewed Original ResearchRisk of DKADuke Clinical Research InstituteC-pepC-peptidePolygenic scoresClinical Research InstitutePopulation Health Research InstituteHigh-risk ptsFasting C-peptideHealth Research InstituteCV outcome trialsAmerican College of CardiologyHigher-risk groupsPredicting DKAType 2 diabetesCSL BehringDiabetic ketoacidosisFerring PharmaceuticalsBristol-Myers SquibbSt. Jude MedicalNon-HLAIncreased riskCleveland ClinicDapagliflozinAmerican College
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